Depression: Tests, symptoms, causes, and treatment

 

depression article

Explore information about depression (also known as depressive disorder or clinical depression), including signs and symptoms, treatment, research and statistics, and clinical trials. Examples of depressive disorders include persistent depressive disorder, postpartum depression (PPD), and seasonal affective disorder (SAD). Mar 05,  · You have chosen to share the following article: How elderberries can help you fight the flu. To proceed, simply complete the form below, and a link to the article . The Depression page contains articles and information from the New England Journal of Medicine.


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We do not store details you enter into this form. Please see our privacy policy for more information. Click here to return to the Medical News Today home page. For some people, depression might only be episodic and overcome within a matter of weeks or months.

However, for others diagnosed with major depressionthe condition could persist for years, affecting their lifestyle and quality of life. Looking at depression article in which major depression lasts for over a decade, researchers from the Centre for Addiction and Mental Health CAMH in Ontario, Canada wanted to investigate whether living with this condition for so long would significantly impact the brain, and if so, depression article, how.

He and his team compared the brain scans of people who had lived with untreated depression for 10 years or longer with those of people with a shorter history of depression. The findings — published last week in The Lancet Psychiatry — suggest that specialists might want to change their approach to treating long-term depression as it progresses to match its increasing neurological impact.

Meyer and team worked with 80 people aged 18— Of these, 25 had lived with depression for longer than 10 years, 25 had had the condition for less than a depression article, and 30 were depression-free. This final cohort made up the control depression article. In a study fromDr. Depression article and his colleagues saw that during episodes of major depression, people's brains would exhibit markers of inflammation.

Based on that knowledge, in the new study, he wanted to explore whether the brain inflammation worsened over time in people depression article long-lasting depression. The scientists determined the severity of the neuroinflammation using a type of brain scan known as depression article emission tomography PET. This allowed them to monitor the activity of microglia, a type of cell found in the central nervous systemwhich are associated with the inflammatory response to injury.

Active microglia produce translocator protein TSPOwhich is a key marker of inflammation. Through the PET scans, Dr. Meyer and team found that the concentration of TSPO was 29—33 percent higher in the brains of people who had lived with depression for more than a decade. These inflammation markers were seen in three brain regions in particular: the prefrontal cortex, the anterior cingulate cortex, and the insula, depression article.

Consistent with previous findings, depression article, the brains of those who had lived with untreated depression for shorter periods of time still had higher concentrations of TSPO than the brains of healthy controls.

According to the researchers, depression article, these results suggest that long-term depression should be treated as a different stage of the same condition, as it may require a different therapeutic approach than depression in its earlier phases, depression article. This, they add, depression article, is similar to the strategy applied in the case of neurodegenerative diseases, which are also depression article by heightened brain inflammation.

If depression, although not a neurodegenerative disease, is similar to such conditions — that is, characterized by an increasingly serious inflammatory response in the brain — then it may be adequate to treat it with anti-inflammatory drugs, Dr.

Meyer suggests. Therefore, depression article, he argues that further studies should look into the possibility of repurposing such medication as therapy for depression. Another question that should be answered, depression article, he concludes, is what the best therapy for people with long-term major depression might be, depression article, since this specific population does not usually benefit from dedicated studies.

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By Maria Cohut. Fact checked by Jasmin Collier. When depression doesn't loosen its grip for a decade, how does it impact the brain? Understanding anhedonia: What happens in the brain? Anhedonia, or loss of pleasure in usually enjoyable activities, is often associated with depression. What are the underlying mechanisms?

Related coverage. Latest news How do superstitions affect our psychology and well-being? This Friday the 13th, we take a look at the psychological mechanisms of superstitions and their effect on depression article health and well-being. Calorie restriction plus exercise can make bones more fragile. New research in female mice reveals that exercising while on a low calorie diet can decrease quality and quantity of bone instead of increasing robustness. E-cigarette vapors, even without nicotine, depression article, may harm lungs.

New research in mice finds that even nicotine free vaping may harm lung function by causing an abnormal buildup of lipids and harming immune cells. Why do female bonobos have more sex with each other than with males? Female bonobos have frequent sexual interactions with other females — more so than they do with depression article. A new study aims to find out why. Fight-or-flight: Do our bones play a part?

A new study in humans and animals identifies the bone hormone osteocalcin depression article a crucial depression article for the fight-or-flight survival response.

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Depression: Causes, Symptoms, Treatment & News | Everyday Health

 

depression article

 

Mar 05,  · You have chosen to share the following article: How elderberries can help you fight the flu. To proceed, simply complete the form below, and a link to the article . May 14,  · Learn about depression symptoms in men, women, teenagers, and children. Plus, read about treatment, medications and side effects, causes, and diagnosis. One in 10 people will have some type of depression during their lifetime. Most people feel sad or depressed at times. It’s a normal reaction to loss or life's struggles. But when intense sadness -- including feeling helpless, hopeless, and worthless -- lasts for many Author: Debra Fulghum Bruce, Phd.